Human NAT1 activation kit by CRISPRa

CAT#: GA100003

NAT1 CRISPRa kit - CRISPR gene activation of human N-acetyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NAT1
• Locus ID: 9
• Kit Components:

  GA100003G1, NAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100003G2, NAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100003G3, NAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000662, NM_001160170, NM_001160171, NM_001160172, NM_001160173, NM_001160174, NM_001160175, NM_001160176, NM_001160179, NM_001291962, NM_001291962.2
• Synonyms: AAC1; MNAT; NAT-1; NATI
• Summary: This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]