Human ABP1 (AOC1) activation kit by CRISPRa

CAT#: GA100018

AOC1 CRISPRa kit - CRISPR gene activation of human amine oxidase copper containing 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AOC1
• Locus ID: 26
• Kit Components:

  GA100018G1, ABP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100018G2, ABP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100018G3, ABP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001091, NM_001272072
• Synonyms: ABP; ABP1; DAO; DAO1; KAO
• Summary: This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]