Human ABL2 activation kit by CRISPRa

CAT#: GA100019

ABL2 CRISPRa kit - CRISPR gene activation of human ABL proto-oncogene 2, non-receptor tyrosine kinase

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Frequently bought together (1)
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    • 100 ul

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol ABL2
Locus ID 27
Kit Components

GA100019G1, ABL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100019G2, ABL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100019G3, ABL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001100108, NM_001136000, NM_001136001, NM_001168236, NM_001168237, NM_001168238, NM_001168239, NM_005158, NM_007314
Synonyms ABLL; ARG; FLJ22224; FLJ31718; FLJ41441
Summary 'This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.