Human ADAM10 activation kit by CRISPRa

CAT#: GA100066

ADAM10 CRISPRa kit - CRISPR gene activation of human ADAM metallopeptidase domain 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADAM10
• Locus ID: 102
• Kit Components:

  GA100066G1, ADAM10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100066G2, ADAM10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100066G3, ADAM10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001110, NM_001320570
• Synonyms: AD10; AD18; CD156c; HsT18717; kuz; MADM; RAK
• Summary: 'Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016]'