Human PACAP receptor (ADCYAP1R1) activation kit by CRISPRa

CAT#: GA100079

ADCYAP1R1 CRISPRa kit - CRISPR gene activation of human ADCYAP receptor type I

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADCYAP1R1
• Locus ID: 117
• Kit Components:

  GA100079G1, PACAP receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100079G2, PACAP receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100079G3, PACAP receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001118, NM_001199635, NM_001199636, NM_001199637
• Synonyms: PAC1; PAC1R; PACAPR; PACAPRI
• Summary: 'This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]'