Human Adenosine A3 Receptor (ADORA3) activation kit by CRISPRa

CAT#: GA100096

ADORA3 CRISPRa kit - CRISPR gene activation of human adenosine A3 receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADORA3
• Locus ID: 140
• Kit Components:

  GA100096G1, Adenosine A3 Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100096G2, Adenosine A3 Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100096G3, Adenosine A3 Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000677, NM_001302678, NM_001302679, NM_001302678.2, NM_001302679.2
• Synonyms: A3AR
• Summary: 'This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014]'