Human ADPRH activation kit by CRISPRa

CAT#: GA100097

ADPRH CRISPRa kit - CRISPR gene activation of human ADP-ribosylarginine hydrolase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADPRH
• Locus ID: 141
• Kit Components:

  GA100097G1, ADPRH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100097G2, ADPRH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100097G3, ADPRH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001125, NM_001291949, NM_001291950, NM_001291950.2
• Synonyms: ARH1
• Summary: 'The enzyme encoded by this gene catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. Unlike the rat and mouse enzymes that require DTT for maximal activity, the human enzyme is DTT-independent. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, May 2014]'