Human beta 1 Adrenergic Receptor (ADRB1) activation kit by CRISPRa

CAT#: GA100106

ADRB1 CRISPRa kit - CRISPR gene activation of human adrenoceptor beta 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADRB1
• Locus ID: 153
• Kit Components:

  GA100106G1, beta 1 Adrenergic Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100106G2, beta 1 Adrenergic Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100106G3, beta 1 Adrenergic Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000684
• Synonyms: ADRB1R; B1AR; BETA1AR; RHR
• Summary: 'The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Sep 2019]'