Human beta 3 Adrenergic Receptor (ADRB3) activation kit by CRISPRa

CAT#: GA100108

ADRB3 CRISPRa kit - CRISPR gene activation of human adrenoceptor beta 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADRB3
• Locus ID: 155
• Kit Components:

  GA100108G1, beta 3 Adrenergic Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100108G2, beta 3 Adrenergic Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100108G3, beta 3 Adrenergic Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000025
• Synonyms: BETA3AR
• Summary: 'The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]'