Human AGRP activation kit by CRISPRa

CAT#: GA100127

AGRP CRISPRa kit - CRISPR gene activation of human agouti related neuropeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AGRP
• Locus ID: 181
• Kit Components:

  GA100127G1, AGRP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100127G2, AGRP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100127G3, AGRP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001138, NM_007316
• Synonyms: AGRT; ART; ASIP2
• Summary: 'This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]'