AGRP Rabbit Polyclonal Antibody

CAT#: TA323216

Anti-AGRP Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 50-63 amino acids of human agouti related protein homolog (mouse)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: agouti related neuropeptide
• Database Link:
  NP_001129
  Entrez Gene 11604 MouseEntrez Gene 25582 RatEntrez Gene 181 Human
  UniProt ID O00253
• Background: This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation; and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
• Synonyms: AGRT; ART; ASIP2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Adipocytokine signaling pathway