Human Iba1 (AIF1) activation kit by CRISPRa

CAT#: GA100138

AIF1 CRISPRa kit - CRISPR gene activation of human allograft inflammatory factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AIF1
• Locus ID: 199
• Kit Components:

  GA100138G1, Iba1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100138G2, Iba1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100138G3, Iba1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318970, NM_001623, NM_004847, NM_032955
• Synonyms: AIF-1; IBA1; IRT-1; IRT1
• Summary: 'This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]'