Human Adenylate Kinase 1 (AK1) activation kit by CRISPRa

CAT#: GA100140

AK1 CRISPRa kit - CRISPR gene activation of human adenylate kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AK1
• Locus ID: 203
• Kit Components:

  GA100140G1, Adenylate Kinase 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100140G2, Adenylate Kinase 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100140G3, Adenylate Kinase 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000476, NM_001318121, NM_001318122
• Synonyms: HTL-S-58j
• Summary: 'This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]'