Human CD166 (ALCAM) activation kit by CRISPRa

CAT#: GA100149

ALCAM CRISPRa kit - CRISPR gene activation of human activated leukocyte cell adhesion molecule

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALCAM
• Locus ID: 214
• Kit Components:

  GA100149G1, CD166 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100149G2, CD166 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100149G3, CD166 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243280, NM_001243281, NM_001243283, NM_001627
• Synonyms: CD166; MEMD
• Summary: 'This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]'