Human Alkaline Phosphatase (ALPI) activation kit by CRISPRa

CAT#: GA100172

ALPI CRISPRa kit - CRISPR gene activation of human alkaline phosphatase, intestinal

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALPI
• Locus ID: 248
• Kit Components:

  GA100172G1, Alkaline Phosphatase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100172G2, Alkaline Phosphatase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100172G3, Alkaline Phosphatase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001631
• Synonyms: IAP
• Summary: 'There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut. [provided by RefSeq, Dec 2014]'