Human Alpha 1 microglobulin (AMBP) activation kit by CRISPRa

CAT#: GA100178

AMBP CRISPRa kit - CRISPR gene activation of human alpha-1-microglobulin/bikunin precursor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMBP
• Locus ID: 259
• Kit Components:

  GA100178G1, Alpha 1 microglobulin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100178G2, Alpha 1 microglobulin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100178G3, Alpha 1 microglobulin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001633
• Synonyms: A1M; EDC1; HCP; HI30; IATIL; ITI; ITIL; ITILC; UTI
• Summary: 'This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]'