Human AMFR activation kit by CRISPRa

CAT#: GA100182

AMFR CRISPRa kit - CRISPR gene activation of human autocrine motility factor receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMFR
• Locus ID: 267
• Kit Components:

  GA100182G1, AMFR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100182G2, AMFR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100182G3, AMFR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001144, NM_001323511, NM_001323512, NM_138958
• Synonyms: GP78; RNF45
• Summary: 'This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins. [provided by RefSeq, Feb 2012]'