Human Amphiphysin (AMPH) activation kit by CRISPRa

CAT#: GA100188

AMPH CRISPRa kit - CRISPR gene activation of human amphiphysin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMPH
• Locus ID: 273
• Kit Components:

  GA100188G1, Amphiphysin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100188G2, Amphiphysin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100188G3, Amphiphysin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001635, NM_139316
• Synonyms: AMPH1
• Summary: 'This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Nov 2010]'