Human Annexin VI (ANXA6) activation kit by CRISPRa

CAT#: GA100211

ANXA6 CRISPRa kit - CRISPR gene activation of human annexin A6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ANXA6
• Locus ID: 309
• Kit Components:

  GA100211G1, Annexin VI gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100211G2, Annexin VI gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100211G3, Annexin VI gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001155, NM_001193544, NM_004033, NM_001363114
• Synonyms: ANX6; CBP68
• Summary: 'Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]'