Human BIRC5 activation kit by CRISPRa

CAT#: GA100233

BIRC5 CRISPRa kit - CRISPR gene activation of human baculoviral IAP repeat containing 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BIRC5
• Locus ID: 332
• Kit Components:

  GA100233G1, BIRC5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100233G2, BIRC5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100233G3, BIRC5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012270, NM_001012271, NM_001168
• Synonyms: API4; EPR-1
• Summary: 'This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]'