Human A RAF (ARAF) activation kit by CRISPRa

CAT#: GA100265

ARAF CRISPRa kit - CRISPR gene activation of human A-Raf proto-oncogene, serine/threonine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARAF
• Locus ID: 369
• Kit Components:

  GA100265G1, A RAF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100265G2, A RAF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100265G3, A RAF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256196, NM_001256197, NM_001654
• Synonyms: A-RAF; ARAF1; PKS2; RAFA1
• Summary: 'This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2012]'