Human ARF3 activation kit by CRISPRa

CAT#: GA100270

ARF3 CRISPRa kit - CRISPR gene activation of human ADP ribosylation factor 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARF3
• Locus ID: 377
• Kit Components:

  GA100270G1, ARF3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100270G2, ARF3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100270G3, ARF3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001659
• Synonyms: ADP-ribosylation factor 3; ADP-ribosylation factor protein 3; small GTP binding protein
• Summary: 'ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns. [provided by RefSeq, Jul 2008]'