Human ARSB activation kit by CRISPRa

CAT#: GA100300

ARSB CRISPRa kit - CRISPR gene activation of human arylsulfatase B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARSB
• Locus ID: 411
• Kit Components:

  GA100300G1, ARSB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100300G2, ARSB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100300G3, ARSB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000046, NM_198709
• Synonyms: ASB; G4S; MPS6
• Summary: 'Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2016]'