Human ASS1 activation kit by CRISPRa

CAT#: GA100321

ASS1 CRISPRa kit - CRISPR gene activation of human argininosuccinate synthase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ASS1
• Locus ID: 445
• Kit Components:

  GA100321G1, ASS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100321G2, ASS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100321G3, ASS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000050, NM_054012
• Synonyms: ASS; CTLN1
• Summary: 'The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2012]'