Human RERE activation kit by CRISPRa

CAT#: GA100330

RERE CRISPRa kit - CRISPR gene activation of human arginine-glutamic acid dipeptide repeats

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RERE
• Locus ID: 473
• Kit Components:

  GA100330G1, RERE gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100330G2, RERE gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100330G3, RERE gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042681, NM_001042682, NM_012102
• Synonyms: ARG; ARP; ATN1L; DNB1; NEDBEH
• Summary: 'This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'