Human AVPR1A activation kit by CRISPRa

CAT#: GA100382

AVPR1A CRISPRa kit - CRISPR gene activation of human arginine vasopressin receptor 1A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AVPR1A
• Locus ID: 552
• Kit Components:

  GA100382G1, AVPR1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100382G2, AVPR1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100382G3, AVPR1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000706
• Synonyms: AVPR1; AVPR V1a; V1aR
• Summary: 'The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]'