Human beta 2 Microglobulin (B2M) activation kit by CRISPRa

CAT#: GA100388

B2M CRISPRa kit - CRISPR gene activation of human beta-2-microglobulin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: B2M
• Locus ID: 567
• Kit Components:

  GA100388G1, beta 2 Microglobulin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100388G2, beta 2 Microglobulin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100388G3, beta 2 Microglobulin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004048
• Synonyms: IMD43
• Summary: 'This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]'