Human BAAT activation kit by CRISPRa

CAT#: GA100389

BAAT CRISPRa kit - CRISPR gene activation of human bile acid-CoA:amino acid N-acyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BAAT
• Locus ID: 570
• Kit Components:

  GA100389G1, BAAT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100389G2, BAAT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100389G3, BAAT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127610, NM_001701
• Synonyms: BACAT; BAT
• Summary: 'The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'