Human BCL2 activation kit by CRISPRa

CAT#: GA100410

BCL2 CRISPRa kit - CRISPR gene activation of human BCL2 apoptosis regulator

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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol BCL2
Locus ID 596
Kit Components

GA100410G1, BCL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100410G2, BCL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100410G3, BCL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000633, NM_000657
Synonyms Bcl-2; PPP1R50
Summary 'This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.