Human HCN2 activation kit by CRISPRa

CAT#: GA100419

HCN2 CRISPRa kit - CRISPR gene activation of human hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HCN2
• Locus ID: 610
• Kit Components:

  GA100419G1, HCN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100419G2, HCN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100419G3, HCN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001194
• Synonyms: BCNG-2; BCNG2; HAC-1
• Summary: 'The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]'