Human BDH1 activation kit by CRISPRa

CAT#: GA100423

BDH1 CRISPRa kit - CRISPR gene activation of human 3-hydroxybutyrate dehydrogenase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BDH1
• Locus ID: 622
• Kit Components:

  GA100423G1, BDH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100423G2, BDH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100423G3, BDH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004051, NM_203314, NM_203315
• Synonyms: BDH; SDR9C1
• Summary: 'This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]'