Human BIK activation kit by CRISPRa
CAT#: GA100435
BIK CRISPRa kit - CRISPR gene activation of human BCL2 interacting killer
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | BIK |
Locus ID | 638 |
Kit Components | GA100435G1, BIK gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100435G2, BIK gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100435G3, BIK gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001197 |
Synonyms | BIP1; BP4; NBK |
Summary | The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN400546 | BIK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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