Human PRDM1 activation kit by CRISPRa

CAT#: GA100436

PRDM1 CRISPRa kit - CRISPR gene activation of human PR/SET domain 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRDM1
• Locus ID: 639
• Kit Components:

  GA100436G1, PRDM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100436G2, PRDM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100436G3, PRDM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001198, NM_182907
• Synonyms: BLIMP1; PRDI-BF1
• Summary: 'This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]'