Human BNIP1 activation kit by CRISPRa

CAT#: GA100458

BNIP1 CRISPRa kit - CRISPR gene activation of human BCL2 interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BNIP1
• Locus ID: 662
• Kit Components:

  GA100458G1, BNIP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100458G2, BNIP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100458G3, BNIP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001205, NM_013978, NM_013979, NM_013980
• Synonyms: NIP1; SEC20; TRG-8
• Summary: 'This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini. [provided by RefSeq, Mar 2011]'