Human BNIP3 activation kit by CRISPRa

CAT#: GA100460

BNIP3 CRISPRa kit - CRISPR gene activation of human BCL2 interacting protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BNIP3
• Locus ID: 664
• Kit Components:

  GA100460G1, BNIP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100460G2, BNIP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100460G3, BNIP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004052
• Synonyms: NIP3
• Summary: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014]