Human BNIP3L activation kit by CRISPRa

CAT#: GA100461

BNIP3L CRISPRa kit - CRISPR gene activation of human BCL2 interacting protein 3 like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BNIP3L
• Locus ID: 665
• Kit Components:

  GA100461G1, BNIP3L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100461G2, BNIP3L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100461G3, BNIP3L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004331, NM_001330491
• Synonyms: BNIP3a; NIX
• Summary: 'This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]'