Human Bone marrow stromal cell antigen 1 (BST1) activation kit by CRISPRa

CAT#: GA100476

BST1 CRISPRa kit - CRISPR gene activation of human bone marrow stromal cell antigen 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BST1
• Locus ID: 683
• Kit Components:

  GA100476G1, Bone marrow stromal cell antigen 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100476G2, Bone marrow stromal cell antigen 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100476G3, Bone marrow stromal cell antigen 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004334
• Synonyms: CD157
• Summary: 'Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]'