Human BTG1 activation kit by CRISPRa

CAT#: GA100483

BTG1 CRISPRa kit - CRISPR gene activation of human BTG anti-proliferation factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BTG1
• Locus ID: 694
• Kit Components:

  GA100483G1, BTG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100483G2, BTG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100483G3, BTG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001731
• Synonyms: APRO2
• Summary: 'This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]'