Human SERPING1 activation kit by CRISPRa

CAT#: GA100491

SERPING1 CRISPRa kit - CRISPR gene activation of human serpin family G member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SERPING1
• Locus ID: 710
• Kit Components:

  GA100491G1, SERPING1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100491G2, SERPING1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100491G3, SERPING1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000062, NM_001032295
• Synonyms: C1IN; C1INH; C1NH; HAE1; HAE2
• Summary: 'This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, May 2020]'