Human C1R activation kit by CRISPRa

CAT#: GA100495

C1R CRISPRa kit - CRISPR gene activation of human complement C1r

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: C1R
• Locus ID: 715
• Kit Components:

  GA100495G1, C1R gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100495G2, C1R gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100495G3, C1R gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001733, NM_001354346
• Synonyms: complement component 1, r subcomponent
• Summary: 'This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome. [provided by RefSeq, Dec 2018]'