Human C1S activation kit by CRISPRa

CAT#: GA100496

C1S CRISPRa kit - CRISPR gene activation of human complement C1s

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: C1S
• Locus ID: 716
• Kit Components:

  GA100496G1, C1S gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100496G2, C1S gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100496G3, C1S gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001734, NM_201442, NM_001346850
• Synonyms: FLJ44757
• Summary: 'This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]'