Human Calpain 5 (CAPN5) activation kit by CRISPRa

CAT#: GA100504

CAPN5 CRISPRa kit - CRISPR gene activation of human calpain 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CAPN5
• Locus ID: 726
• Kit Components:

  GA100504G1, Calpain 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100504G2, Calpain 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100504G3, Calpain 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004055
• Synonyms: ADNIV; HTRA3; nCL-3; VRNI
• Summary: 'Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008]'