Human Complement C9 (C9) activation kit by CRISPRa

CAT#: GA100513

C9 CRISPRa kit - CRISPR gene activation of human complement C9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: C9
• Locus ID: 735
• Kit Components:

  GA100513G1, Complement C9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100513G2, Complement C9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100513G3, Complement C9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001737
• Synonyms: ARMD15; C9D
• Summary: 'This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]'