Human CA5A activation kit by CRISPRa

CAT#: GA100531

CA5A CRISPRa kit - CRISPR gene activation of human carbonic anhydrase 5A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CA5A
• Locus ID: 763
• Kit Components:

  GA100531G1, CA5A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100531G2, CA5A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100531G3, CA5A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001739, NM_001367225, NR_159799, NR_159798
• Synonyms: CA5; CA5AD; CAV; CAVA
• Summary: ' Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008]'