Human CACNA1F activation kit by CRISPRa

CAT#: GA100543

CACNA1F CRISPRa kit - CRISPR gene activation of human calcium voltage-gated channel subunit alpha1 F

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CACNA1F
• Locus ID: 778
• Kit Components:

  GA100543G1, CACNA1F gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100543G2, CACNA1F gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100543G3, CACNA1F gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256789, NM_001256790, NM_005183
• Synonyms: AIED; Cav1.4; Cav1.4alpha1; COD3; COD4; CORDX; CORDX3; CSNB2; CSNB2A; CSNBX2; JM8; JMC8; OA2
• Summary: 'This gene encodes a multipass transmembrane protein that functions as an alpha-1 subunit of the voltage-dependent calcium channel, which mediates the influx of calcium ions into the cell. The encoded protein forms a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Mutations in this gene can cause X-linked eye disorders, including congenital stationary night blindness type 2A, cone-rod dystropy, and Aland Island eye disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2013]'