Human CACNB1 activation kit by CRISPRa

CAT#: GA100547

CACNB1 CRISPRa kit - CRISPR gene activation of human calcium voltage-gated channel auxiliary subunit beta 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CACNB1
• Locus ID: 782
• Kit Components:

  GA100547G1, CACNB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100547G2, CACNB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100547G3, CACNB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000723, NM_199247, NM_199248
• Synonyms: CAB1; CACNLB1; CCHLB1
• Summary: 'The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]'