Human CACNB2 activation kit by CRISPRa

CAT#: GA100548

CACNB2 CRISPRa kit - CRISPR gene activation of human calcium voltage-gated channel auxiliary subunit beta 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CACNB2
• Locus ID: 783
• Kit Components:

  GA100548G1, CACNB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100548G2, CACNB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100548G3, CACNB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000724, NM_001167945, NM_201570, NM_201571, NM_201572, NM_201590, NM_201593, NM_201596, NM_201597, NM_001330060
• Synonyms: CACNLB2; CAVB2; MYSB
• Summary: 'This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]'