Human Calretinin (CALB2) activation kit by CRISPRa

CAT#: GA100555

CALB2 CRISPRa kit - CRISPR gene activation of human calbindin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CALB2
• Locus ID: 794
• Kit Components:

  GA100555G1, Calretinin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100555G2, Calretinin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100555G3, Calretinin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001740, NM_007087, NM_007088, NR_027910
• Synonyms: CAB29; CAL2; CR
• Summary: 'This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]'