Human CALM1 activation kit by CRISPRa

CAT#: GA100561

CALM1 CRISPRa kit - CRISPR gene activation of human calmodulin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CALM1
• Locus ID: 801
• Kit Components:

  GA100561G1, CALM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100561G2, CALM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100561G3, CALM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166106, NM_006888, NM_001363669, NM_001363670
• Synonyms: CALM2; CALM3; CALML2; CAMI; DD132; PHKD
• Summary: 'This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.[provided by RefSeq, May 2020]'