Human CAMK2G activation kit by CRISPRa

CAT#: GA100571

CAMK2G CRISPRa kit - CRISPR gene activation of human calcium/calmodulin dependent protein kinase II gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CAMK2G
• Locus ID: 818
• Kit Components:

  GA100571G1, CAMK2G gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100571G2, CAMK2G gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100571G3, CAMK2G gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204492, NM_001222, NM_001320898, NM_172169, NM_172170, NM_172171, NM_172172, NM_172173, NM_001367547, NM_001367516, NM_001367518, NM_001367525, NM_001367526, NM_001367529, NM_001367534, NM_001367537, NM_001367539, NM_001367540, NM_001367542, NM_001367544, NM_001367545, NR_160042, NR_160045, NR_160263, NM_001367514, NM_001367517, NM_001367519, NM_001367520, NM_001367521, NM_001367522, NM_001367523, NM_001367524, NM_001367527, NM_001367528, NM_001367530, NM_001367531, NM_001367532, NM_001367533, NM_001367535, NM_001367536, NM_001367538, NM_001367541, NM_001367543, NM_001367546, NM_001367548, NR_160040, NR_160041, NR_160044, NR_160046, NR_160047
• Synonyms: CAMK; CAMK-II; CAMKG
• Summary: 'The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]'